Kidney and Blood Pressure Regulation
By:"Hiromichi Suzuki (M.D.)","Takao Saruta"
Published on 2004 by Karger Medical and Scientific Publishers
This ebook tells about Chronic kidney disease is one of the world's major public health problems, and the prevalence of kidney failure is rising steadily. Among the risk factors for a faster progression of renal disease are hypertension and proteinuria, many studies clearly demonstrating that hypertension is both a cause and consequence of chronic kidney disease. Namely, renal blood pressure regulation seems to be involved in five major pathophysiological mechanisms (all closely related to the renin-angiotensin system): Pressure-natriuresis, renal sympathetic nervous system, renal blood flow, intraglomerular pressure and tubuloglomerular feedback. This book reviews experimental data which form the basis of our current understanding of the association between hypertension and kidney diseases: The pathogenesis of increased blood pressure, the mechanisms by which systemic hypertension promotes progressive kidney failure, and the impact of antihypertensive agents on experimental renal mechanisms involved in hypertension. Furthermore, the role of angiotensin II receptor blockers in both the control of systemic blood pressure and the reduction of proteinuria is examined in an attempt to define optimal therapeutic strategies to prevent the otherwise inexorable deterioration of renal function in patients with chronic kidney disease.
This Book was ranked 23 by Google Books for keyword Blood Pressure Effects.
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Kidney and Blood Pressure Regulation
Suzuki H, Saruta T (eds): Kidney and \u003cb\u003eBlood Pressure\u003c/b\u003e Regulation. ... II plays a \u003cbr\u003e\npathophysiological role in the progression of chronic kidney disease and its \u003cbr\u003e\ninhibition and control is, without doubt, crucial in the control of its damaging \u003cbr\u003e\n\u003cb\u003eeffects\u003c/b\u003e.
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